Vance Spencer
Vance Spencer is the co-founder of Framework Ventures, the venture firm he built with Michael Anderson that was arguably the first VC to go all in on DeFi, notching early investments in Chainlink, Synthetix, Aave, and The Graph. Before Framework, the pair built and sold Hashletes, a digital collectibles startup with official NFL licensing, and before crypto Spencer worked at Netflix in Los Angeles and Tokyo, helping relaunch the Japan business and later joining corporate development for northern Asia. He is a regular voice on Blockworks programming, co-hosting Bell Curve and the Framework-backed weekly show Oneshot, where he works through market structure, macro, and the business of onchain finance.
134 talks by Vance Spencer
- Oneshot: Tempo Mainnet, Agentic Payments, and SEC Crypto Rulemaking | Roundup
- Oneshot: Market Uncertainty, AI Valuations, and Crypto’s Path Forward | Roundup
- Oneshot: The Bill That Could Reshape Crypto | Rebecca Rettig
- Introducing Oneshot: The AI Arms Race and Crypto Market Consolidation | Michael & Vance
- Market Structure, Macro Volatility, and the Next Phase of Crypto | Michael Anderson & Vance Spencer
- The Neo Finance Bull Thesis with Vance Spencer & Michael Anderson
- Jordi Alexander, AI Supercycle EP 15, Tristan from Bullet, Vance & Michael from Framework
- 2026 Predictions with Michael Anderson and Vance Spencer
- The 4 Year Cycle Is Dead - Michael Anderson and Vance Spencer
- Revenue Meta, RWA Looping & Uniswap Fee Switch | Roundup
- Why Wall Street Believes Next Bull Market is Already Here with Vance Spencer and Michael Anderson
- Gold Hits All-Time Highs, Stablecoin Adoption, and Historic Liquidations | Roundup
- The $40B Liquidation That Exposed Crypto's Biggest Problem - Framework Founders
- Bitcoin Seasonality, Capital Flows, and New Stablecoins | Roundup
- Ethereum’s Next Step, HYPE’s Token Supply, and Tether’s Big Raise | Roundup
- DATs, Stablecoin Wars, and Corporate Chains | Roundup
- The Hyperliquid Stablecoin Wars: How $200M in Profits Could Change DeFi with Vance Spencer
- The Rollup TV: Hyperliquid USDH Special Day 2
- GPT-5, Trump’s Crypto Executive Order, and Ethereum’s Bullish Saga | Roundup
- Ethereum’s Comeback, PumpFun’s ICO, and Crypto’s Regulatory Shift | Roundup
- Macro Uncertainty, Circle’s Surge, and Prediction Market Utility | Roundup
- PumpFun’s Impact on Solana, Circle’s IPO, and Elon and Trump’s Feud | Roundup
- OpenAI, Hyperliquid, and the Internet's Next Growth Phase | Roundup
- Ethereum Is Running Away With DeFi | Roundup